Basic resarch into human embryonic development.Continue Reading
Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos
We have generated whole genome expression data (RNA-seq) from 15 tissues sampled during human embryogenesis. For most tissues, it is the earliest known measurement and considerably earlier than the fetal tissues of the NIH Roadmap project.
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A wealth of data and comprehensive reviews exist on pancreas development in mammals, primarily mice, and other vertebrates. By contrast, human pancreatic development has been less comprehensively reviewed. Here, we draw together those studies conducted directly in human embryonic and fetal tissue to provide an overview of ...